HIGHLIGHTS
What stands out in this treatment
OVERVIEW
Who it's for & conditions treated
Who is it for?
An enlarged lymph node or a palpable mass of uncertain origin.
Organ involvement (liver, lung, bone) detected on imaging without an identifiable primary.
Unexplained weight loss, fatigue and deterioration in general condition.
Region-dependent pain, fullness or signs of organ dysfunction.
Signs of spread such as abdominal fluid (ascites) or fluid in the lung lining (pleural effusion).
Detection of metastatic cancer on a biopsy performed for another reason, without a known primary.
Conditions treated
Comprehensive Imaging and StagingOrigin Investigation with ImmunohistochemistryMolecular Profiling / Gene ExpressionSystemic Therapy Directed at the Likely PrimaryLocal Control — Surgery and RadiotherapyMultidisciplinary Oncology Council
TREATMENTS
Our treatment methods
Cancer of Unknown Primary (CUP)
For cancer of unknown primary (CUP), the path forward comes from thorough workup and board review. Our Doruk Oncology team walks it with you.
TREATMENT TIMELINE
From day one to discharge
The timeline below is an average and varies by patient, diagnosis and clinical status. Exact timing and all included services are detailed in your personalized treatment offer.
Step 1
Application and comprehensive imaging — Existing biopsy, images and reports are shared; assessment is led by PET-CT.
Step 2
Pathology and immunohistochemistry — Origin investigation in the metastatic tissue with a broad immunohistochemistry panel.
Step 3
Molecular profiling / gene expression — Estimation of the likely origin and identification of molecular targets.
Step 4
The council’s central decision and personalized plan — All findings are reviewed in the council; origin-directed systemic therapy and, if needed, local control are planned.
Step 5
Treatment and follow-up — The plan is delivered; follow-up with response assessment, re-imaging and tele-oncology support.
Every treatment offer is presented in full detail — accommodation, transfer, interpreter and follow-up included — clearly stating what is covered.
HOW IT WORKS
A completely carefree treatment journey
1
Online application
Fill the form or message us on WhatsApp; share your file in seconds.
2
Free evaluation
Our specialists review your file and reply within 24 hours.
3
Personalized plan
Treatment steps, timeline and transparent cost are clarified.
4
Welcome & treatment
Airport pickup, accommodation and treatment — coordinated end to end.
BY THE NUMBERS
Our center in numbers
12,000+
oncology cases per year at our center
TrueBeam
latest-generation LINAC platform
30+
cancer types treated
PET-CT
for staging and response follow-up
TECHNOLOGY
Our diagnostic and treatment technologies
Technology
WHY DORUK
What sets us apart here
JCI accreditation & patient safety
Accredited to international JCI standards; an independently audited quality and patient-safety system.
Weekly tumor board
Your treatment plan is finalized at a board where medical, radiation and surgical oncology sit together.
Radiotherapy, robotic surgery and PET-CT together
TrueBeam LINAC, Da Vinci robotic surgery and PET-CT in the same center — from tests to treatment without changing institutions.
International patient services
End-to-end support with visa, airport transfer, accommodation and multilingual medical interpreters.
Transparent, guaranteed pricing
A quote prepared from your medical information; the hospital charges no extra for the treatments it covers.
Tele-oncology follow-up
Your post-treatment follow-up continues via tele-oncology after you return home.
INFO & BLOG
About diagnosis, treatment and recovery
What exactly does cancer of unknown primary (CUP) mean?
Why can the primary focus not always be found, and how does this affect treatment?
How do immunohistochemistry and molecular profiling estimate the origin?
How does gene expression analysis contribute to treatment selection?
How are immunotherapy or targeted therapy planned without finding the primary?
In which situations are surgery and radiotherapy considered in CUP?
Why is the council’s role in CUP more decisive than in other cancers?
If the primary focus is later found during treatment, does the plan change?
Which documents and samples (blocks/slides) are needed for a second opinion?
How do the process and follow-up work for international patients?
PRICING
Transparent treatment pricing
Consultation & second opinion
In CUP the process is personalized to origin estimation and the council decision; a transparent quote prepared from your medical information is sent to you.
Free
Radiotherapy course (IMRT)
Planning + sessions included
€4,500 – €8,000
Chemotherapy (per cycle)
Excl. meds, incl. administration
€900 – €2,500
Robotic tumor surgery
3–4 night stay included
€7,500 – €12,000
Indicative price range — your binding quote is sent in writing after your free medical evaluation.
PRICE GUARANTEE
Our quote is a binding commitment
The quote prepared and shared based on the medical information you provide is guaranteed: for every treatment it covers, the hospital charges no extra fees.
Written, binding quote
Your quote is prepared from your medical information and shared in writing.
No surprise charges
For the treatments the quote covers, the hospital requests no extra charge.
All covered treatments included
Every planned treatment is included in the guaranteed price.
PATIENT VOICES
What our patients say
The oncology team was with me medically and emotionally. In a word, they gave me confidence.
Ayşe
Türkiye · Oncology
Illustrative review
All my tests were done in one centre and the tumour board produced a plan the same week.
Klaus
Germany · Oncology
Illustrative review
I came for a second opinion; it was the doctor himself who explained that I should stay and be treated.
Ivan
Bulgaria · Oncology
Illustrative review
A Russian-speaking coordinator was with me at every appointment; I never had to guess anything.
Elena
Russia · Oncology
Illustrative review
The file of the treatment I began at home was read here in full; I did not start from zero.
Aigul
Kazakhstan · Oncology
Illustrative review
Accommodation and transfers were planned in one schedule during radiotherapy; it did not exhaust me.
Faisal
Saudi Arabia · Oncology
Illustrative review
They explained both my illness and my options in my own language. Knowledge eased my fear.
Zainab
Iraq · Oncology
Illustrative review
I had my follow-up calendar in hand after treatment ended; I did not return home into a vacuum.
Sarah
United Kingdom · Oncology
Illustrative review
FAQ
Frequently asked questions
Is the consultation paid?
How do I apply from abroad?
Visa and transfer support?
How is post-care follow-up?